Table 5.
Cox proportional hazards analysis of cancer-specific death and all-causes death for subgroups of CRC patients
Cancer-specific death | All-causes death | |||||
---|---|---|---|---|---|---|
HR | (95% CI) | P value | HR | (95% CI) | P value | |
Panel A: For CRC patients diagnosed after the introduction of the screening program | ||||||
Program participation (Ref. group: Participants of the program) | ||||||
Non-participants of the program | 1.46 | (1.12–1.91) | 0.006 | 1.37 | (1.05–1.77) | 0.019 |
Gender (Ref. group: Female) | ||||||
Male | 1.24 | (1.06–1.45) | 0.008 | 1.23 | (1.05–1.44) | 0.01 |
Age at diagnosis (Ref. group: ≤65 yrs) | ||||||
> 65 yrs | 1.49 | (1.28–1.74) | < 0.001 | 1.49 | (1.28–1.73) | < 0.001 |
Sub-region (Ref. group: Rural) | ||||||
Urban | 0.96 | (0.82–1.12) | 0.589 | 0.95 | (0.81–1.10) | 0.475 |
Level of treatment hospital (Ref. group: Tertiary) | ||||||
Secondary | 1.5 | (1.12–1.91) | < 0.001 | 1.49 | (1.28–1.73) | < 0.001 |
TNM Stage (Ref. group: I + II) | ||||||
III + IV | 1.75 | (1.58–1.94) | < 0.001 | 1.77 | (1.60–1.95) | < 0.001 |
Panel B: For CRC patients who participated in the screening program | ||||||
Screening policy compliance (Ref. group: Compliant to the screening policy) | ||||||
Incompliant to the screening policy | 2.93 | (1.64–5.23) | < 0.001 | 3.29 | (1.85–5.84) | < 0.001 |
Gender (Ref. group: Female) | ||||||
Male | 1.91 | (1.13–3.22) | 0.015 | 1.73 | (1.06–2.84) | 0.029 |
Age at diagnosis (Ref. group: ≤65 yrs) | ||||||
> 65 yrs | 1.11 | (0.67–1.85) | 0.674 | 1.18 | (0.72–1.93) | 0.506 |
Sub-region (Ref. group: Rural) | ||||||
Urban | 0.91 | (0.53–1.56) | 0.718 | 0.86 | (0.51–1.46) | 0.579 |
Level of treatment hospital (Ref. group: Tertiary) | ||||||
Secondary | 1.31 | (0.80–2.14) | 0.283 | 1.34 | (0.84–2.15) | 0.224 |
TNM Stage (Ref. group: I + II) | ||||||
III + IV | 8.55 | (4.54–16.13) | < 0.001 | 7.55 | (4.17–13.55) | < 0.001 |
Notes: Colorectal cancer, CRC; Hazard ratio, HR.