KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Antibodies | ||
| PGDM31400, PG9, VRC38.01, 10–1074, PGT128 | NIH/VRC | N/A |
| PGT135, 2G12, HJ16, IOMA, CH235.12, N6 | NIH/VRC | N/A |
| VRC13.01, b12, CH103, VRC16.01, VRC-PG05 | NIH/VRC | N/A |
| PGT151, VRC34.01, 35O22, 8ANC195, VRC03 | NIH/VRC | N/A |
| Virus Strains | ||
| VRC 208 virus panel | NIH/VRC | N/A |
| Chemicals, Peptides, and Recombinant Proteins | ||
| BG505 DS-SOSIP | NIH/VRC | N/A |
| Deposited Data | ||
| Cryo-EM electron density map of 2G12 in complex with BG505 DS-SOSIP and VRC03 | This Paper | EMD-8981 |
| Fitted coordinates for cryo-EM electron density map of 2G12 in complex with BG505 DS-SOSIP and VRC03 | This Paper | PDB ID: 6E5P |
| Experimental Models: Cell Lines | ||
| Human: TZM-bl cells | NIH AIDS Reagent Program | Cat# 8129; RRID: CVCL_B478 |
| Human: Expi293F cells | Thermo Fisher | Cat# A14527; RRID: CVCL_D615 |
| Recombinant DNA | ||
| pVRC8400 vector | NIH/VRC | N/A |
| Software and Algorithms | ||
| PRISM 7 | GraphPad Software | https://www.graphpad.com/scientific-software/prism/ |
| IMGT V-quest | (Lefranc et al., 2015) | http://www.imgt.org/IMGT_vquest/vquest |
| Pymol | Schrödinger | https://pymol.org |
| R | The R Foundation | https://www.r-project.org |
| Other | ||
| Los Alamos HIV sequence database | LANL | http://www.hiv.lanl.gov/ |