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. 2019 Jul 11;25(7):604–618. doi: 10.1089/tmj.2018.0117

Table 1.

Summary of Study Characteristics and Evidence Map

STUDY DESIGN AUTHOR(S) (YEAR) STUDY GOAL NO. OF ANALYZED FOLLOW-UP UTILIZATION OUTCOMES COST AND FINANCIAL OUTCOMES
ED USE IP/OP VISIT READMIT LENGTH OF STAY OPIOID USE (O) IMAGING USE (I) LAB BED DAY COSTS FINANCIAL METRICS
RCT Neven et al. (2016) To reduce ED visits and decrease controlled substance prescriptions to high utilizers; to assess the ROI of the program Treatment: 79
Control: 76
12 months
+*     O: +*ED + *D   ? +
Rathlev et al. (2016) To assess the impact of electronic alerts on provider opioid prescribing behaviors, patient outcomes, and utilization Treatment: 20
Control: 20
12 months
−IP   O: −ED − IP
+*D
I: −CT/MRI (ED)
   
Ringwalt et al. (2015) To reduce number of ED visits and opioid prescriptions for patients with chronic noncancer pain Treatment: 13
Control: 16
12 months
+*     O: +*
? ED
     
Pre/post Adams and Nielson (2012) To identify recently discharged psychiatric patients revisiting the ED, and to reduce hospital readmissions and ED visits NR
12 months
?            
Chan et al.# (2009) To examine the effect of referral appointment system in the ED on patient access to and adherence with follow-up post-ED visit Pre: 399
Post: 326
6 months
           
Hardin et al. (2017) To reduce healthcare costs and improve outcomes for “high-risk, high-need” patients Pre: 339
Post: 339
12 months
+* +*IP + *OP +* I: +*CT   +* +*
Mercer et al. (2015) To reduce unnecessary healthcare utilization through individualized care plans for high utilizers of ED and inpatient services Pre: 24
Post: 23 (6 months), 12 (12 months)

+* IP + *R
+* IP + *R

    −ED +*IP
−ED +IP
 
Murphy and Neven (2014) To examine the cost-effectiveness of computerized reminders about individualized care plans in the ED Pre: 141
Post: 141
12 months
+* +*IP
+*OP
      +* +*
Stokes-Buzzelli et al. (2010) To examine the use of health IT to manage patients frequently presenting to the ED Pre: 20
Post: 20
24 months
+     +*Lab +  
Stowe (2011) To evaluate the effect of an automated alert system for cancer patients presenting to the ED NR
16 weeks
    ?   ?Bed day ? ?

+* = statistically significant change; + = marginally significant; − = not significant; ? = unclear, p-value not reported. #: study reported significant change in adherence with follow-up.

D, prescribed upon discharge; CT: computed tomography; ED, emergency department, IP, hospital inpatient; MRI, magnetic resonance imaging; NR, not reported; OP, outpatient; R, readmission; RCT, randomized controlled trial; ROI, return on investment.