VACSA 1973.

Methods	Parallel group, placebo‐controlled trial
Participants	541 patients (9 excluded from analysis: 8 hospital withdrew; 1 concurrent malignancy) Country: USA Study years: 1966 to 1970 Age: 70 or under Male: 100% Inclusion: history of cerebral infarction or TIA
Interventions	Clofibrate (500 mg x 4 daily) Matching placebo Follow up: up to 4.5 years
Outcomes	Mortality Cerebral infarction Vascular event
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear