Table S1.
Patient number | Age | Histology | Stage | Fagotti score | CA125 before NLHIPEC | CA125 after NLHIPEC | CA125 after the 3rd NACT | CA125 after IDS | Surgical complexity score groups | R0 resection | Recurrence after primary treatment (recurrent site, time of recurrence) | Treatment of recurrence | Patient status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 65 | Serous | IIIC | 10 | 194 | 49 | 10 | 7 | Intermediate | Yes | No | —— | NED (11 moths) |
2 | 68 | Serous | IIIC | 12 | 803 | 385 | 43 | 33 | Intermediate | Yes | No | —— | NED (15 moths) |
3 | 66 | Serous | IIIC | 8 | 333 | 61 | 12 | 13 | Low | No | No | —— | NED (9 months) |
4 | 70 | Serous | IV | 8 | 989 | 508 | 135 | 81 | Intermediate | Yes | Yes (solitary paraaortic lymph nodes; 13 months) | SCS+chemothrapy (paclitaxel+caboplatin) | NED (19 months) |
5 | 62 | Serous | IV | 8 | 3160 | 1947 | 344 | 32 | Intermediate | No | No | —— | NED (16 months) |
6 | 46 | Serous | IIIC | 8 | 1714 | 343 | 166 | 55 | High | Yes | No | —— | NED (16 months) |
7 | 38 | Serous | IIIC | 10 | 1039 | 114 | 14 | 14 | Intermediate | No | No | —— | NED (21 months) |
8 | 32 | Serous | IV | 8 | 6536 | 1187 | 40 | 8 | Intermediate | No | Yes (solitary pelvic peritoneum, liver; 16 months) | SCS+chemothrapy (paclitaxel+caboplatin) | NED (26 months) |
9 | 53 | Clear cell | IV | 8 | 1220 | 606 | 19 | 19 | Low | No | Yes (extensive intraperitoneal dissemination; 9 months) | Chemothrapy (irinotecan+caboplatin) | Stable disease |
10 | 76 | Serous | IIIC | 12 | 1669 | 48 | 14 | 20 | Intermediate | No | Yes (pelvic peritoneum, multiple lung lesions; 14 months) | Chemothrapy (paclitaxel+caboplatin) followed by Olaparib | Partial response (24 months) |
11 | 62 | Serous | IV | 10 | 720 | 252 | 21 | 7 | low | No | No | —— | NED (13 months) |
12 | 57 | Serous | IIIC | 8 | 3330 | 1414 | 240 | 59 | High | No | No | —— | NED (10 months) |
13 | 32 | Serous | IIIC | 8 | 670 | 133 | 56 | 21 | Intermediate | Yes | Yes (pelvic peritoneum, lung; 11 months) | Chemothrapy (paclitaxel+caboplatin) | Complete response (26 months) |
14 | 69 | Serous | IIIC | 8 | 766 | 101 | 66 | 15 | Intermediate | No | Yes (extensive intraperitoneal dissemination; 18 months) | Chemothrapy (paclitaxel+caboplatin) | Complete response (23 months) |
Abbreviatios: NLHIPEC, neoadjuvant laparoscopic hyperthermic intraperitoneal chemotherapy; NED, no evidence of disease; SCS, secondary cytoreductive surgery.