Figure 3.
Fold change from control (no treatment) of LC3B-II in MDA-MB-231 after exposure to chloroquine (CQ), osimertinib (Osim), and combination (O+CQ). MDA-MB-231 cells exposed to control (Con) as drug-free cell culture medium, CQ (30 μM), Osim (6 μM), or the combination over 24 hrs. LC3B-II and GAPDH were measured using Western blot. Each bar represents a mean from duplicate observed data ± SEM. **p<0.01, ***p<0.001.