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. 2019 Jul 23;9:628. doi: 10.3389/fonc.2019.00628

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Copyright © 2019 Ma, Huang, Tang, Ye, Li, Liu, Mu, Li, Jiang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in the concentrations of CEA in peripheral blood and CSF between day 1 (the initial admission) and day 216. Therapy with afatinib was commenced on day 27.