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. 2009 Oct 21;29(42):13283–13291. doi: 10.1523/JNEUROSCI.3069-09.2009

Figure 3.

Figure 3.

Release of endogenous NO during fictive locomotion. A, Locomotor activity was induced in NMDA (100 μm) in the presence of the NOS inhibitor l-NAME (100 μm). B, Washing out l-NAME resulted in an increase in the frequency of the locomotor rhythm, suggesting a continuous endogenous release of NO. C, Averaged data from all the experiments showing a significant increase in the locomotor frequency upon washout of l-NAME (p < 0.0001, n = 6). D, Averaged data from all the experiments showing a significant increase in the locomotor frequency upon washout of l-NNA (p < 0.0001, n = 4).