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. 2009 Apr 22;29(16):5326–5335. doi: 10.1523/JNEUROSCI.5965-08.2009

Figure 3.

Figure 3.

Rhythmic whisker stimulation induces long-lasting potentiation of whisker-evoked current sinks in the barrel cortex. A, Examples of whisker-evoked LFP recordings in the barrel cortex (left; n = 5 mice) and CSD profiles (right) in the test group at baseline (black traces) and 60 min after 8 Hz whisker stimulation (red traces). Positive LFP voltages and CSD sources are upward going. Roman numerals indicate the approximate limits of cortical layers. Calibration: LFP, 250 μV; CSD, 25 mV/mm2. B, Examples of whisker-evoked LFP recordings (n = 5 mice) and CSD profiles in the control group at baseline and 60 min after sham whisker stimulation. Calibration as in A. C, Averages of selected current sink peak amplitudes at four selected electrodes recorded 30, 60, and 90 min after 8 Hz whisker stimulation, normalized against the baseline. Insets show the averaged CSD traces at the superficial layer II–III, deep layer II–III, layer IV, and layer V–VI border at baseline and 30, 60, and 90 min after 8 Hz stimulation. Traces from controls are not shown. Calibration: horizontal, 10 ms; vertical, 10 mV/mm2 for superficial and deep LII–III and LIV, 2.5 mV/mm2 for LV–VI border. Significant difference from baseline at *p < 0.05 or at **p < 0.01 (double).