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The effect of reversible unilateral inactivation of the mPFC in extinction in the developing rat. A, Histological reconstruction of coronal sections showing cannula placements in the mPFC. □, P17; ●, P24. B, Mean (±SEM) CS-elicited freezing at extinction and test. Unilateral inactivation of the mPFC during extinction disrupted long-term extinction in P24 rats but not in P17 rats. *Significant difference (p < 0.005) from the other groups.
