Skip to main content
. 2009 Jul 22;29(29):9380–9389. doi: 10.1523/JNEUROSCI.0604-09.2009

Figure 4.

Figure 4.

YFP expression in the developing telencephalon of Nkx5-1-Cre;Rosa26R-YFP embryos. A–C, Coronal adjacent sections through the caudal telencephalon of an E13.5 Nkx5-1-Cre;Rosa26R-YFP embryo showing the expression of Shh (A) and Nkx5-1 (B) mRNA and YFP protein (C). In situ images (A, B) were pseudocolored using Photoshop software. YFP expression (C) closely parallels Nkx5-1 mRNA expression in the adjacent section (B). The arrowheads point to cells that seem to follow a dorsal migration from the POA. D–G, Coronal sections through the telencephalon of E15.5 (D, F) and E17.5 (E, G) Nkx5-1-Cre;Rosa26R-YFP embryos showing the distribution of YFP-expressing cells derived from Nkx5-1-expressing cells in the POA. F, G, High-magnification images of the boxed areas shown in D and E, respectively. ac, Anterior commissure; MZ, marginal zone; CP, cortical plate; IZ, intermediate zone; sp, subplate; SVZ, subventricular zone; VZ, ventricular zone; V–VI, cortical layers V and VI. Scale bars: (in A) A–C, 100 μm; D, E, 250 μm; F, 50 μm; G, 100 μm.