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Four month fertility test and epididymal sperm count
| Control | ARNesCre |
||
|---|---|---|---|
| Fertile | Hypofertile | ||
| Fertility | |||
| Total number of pups | 43.2 ± 3.0 (6) | 42.6 ± 1.3 (5) | 22.5 ± 4.2* (4) |
| Total number of litters | 5.8 ± 0.2 (6) | 6.0 ± 0.4 (5) | 4.5 ± 0.9 (4) |
| Litter size | 8.0 ±0.4 (6) | 6.8 ± 0.4* (5) | 5.1 ± 0.6* (4) |
| Sperm count | |||
| No. of spermatozoa (×106/ml) | 14.1 ± 1.1 (26) | 5.8 ± 0.6* (21) | |
Values are means ± SEM of the indicated number (n) of control and ARNesCre mice.
*p < 0.002 versus control.
