Table 2.
Power Analysis for Primary and Secondary Outcome Measuresa
| Outcome Measure | Estimated SD | Difference to Detect | Powerb |
|---|---|---|---|
| Peak quadriceps torque (Nm) | 47 | 39 | 80% |
| Knee extensor moment (Nm/kg) | 0.50 | 0.42 | 81% |
| Knee flexion angle (degrees) | 4.7 | 4 | 82% |
| PCSA (cm2) | 32 | 27 | 82% |
| T1 rho relaxation time (s) | 0.004 | 0.005 | >90% |
| Muscle fiber type (type 2A fiber relative frequency) | 0.09 | 0.08 | 85% |
| Satellite cell abundance (Pax7 + satellite cells/fiber) | 0.05 | 0.05 | >90% |
| Fibroblasts (Tcf4 + fibroblasts/mm2) | 21 | 18 | 83% |
| FAPs (PDGFRα + FAPs/mm2) | 1.3 | 1.1 | 82% |
a
FAPs = fibrogenic/adipogenic progenitors; Pax7 = paired box 7; PCSA = physiological cross-sectional area; PDGFRα = platelet-derived growth factor receptor alpha; Tcf4 = transcription factor 4.
b
Power analyses performed with a sample size of 48 participants and an α = .05