Intact noncholinergic theta rhythms and attenuated cholinergic theta rhythms in PLCβ-4−/− mice. A, Representative EEG waveforms during walking for wild-type mice (WT) and PLC-β4−/− mice (KO). B, Averaged power spectra of the EEG waveforms recorded during walking for wild-type mice (n = 7) and PLC-β4−/− mice (n = 7). C, Representative EEG waveforms during urethane anesthesia for wild-type mice (black trace) and PLC-β4−/− mice (red trace). D, Averaged power spectra of the EEG waveforms recorded during urethane anesthesia for wild-type mice (n = 7) and PLC-β4−/− mice (n = 7). *p < 0.05, two-tailed t test; all data are presented as means ± SEM.