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. 2009 Sep 30;29(39):12244–12254. doi: 10.1523/JNEUROSCI.1970-09.2009

Figure 4.

Figure 4.

Conditioned morphine withdrawal induced Arc protein expression in the amygdala but not in the dorsal hippocampus. Left column, Photomicrographs illustrating Arc protein expression in the amygdala (A) and the DH (C) after either conditioned morphine withdrawal treatment or saline control treatment. Right column, Effects of conditioned morphine withdrawal on the Arc expression of the amygdala (B) and the dorsal hippocampus (D) were determined by immunoblot. The level of Arc expression was normalized to actin level. Values are expressed as mean ± SEM (n = 4–5). *p < 0.05, **p < 0.01, compared with the saline-treated control group, one-way ANOVA with Bonferroni's post hoc test. CMW, Conditioned morphine withdrawal; Con, control; Nal, naloxone; DG, dentate gyrus.