Figure 3.

Effects of melatonin injections on the expression of Dio2 and Dio3 in the ependymal cell layer lining the infundibular recess of the third ventricle of wild-type C57BL mice (WT) and C57BL mice with targeted disruption of MT1 (MT1^−/−). Vehicle (white bars) or melatonin (black bars) were injected 2 h before the light offset under long-day conditions (16 h of light: 8 h of darkness) for 1 week. Asterisks indicate significant differences in each genotype (t test, *p < 0.05; n = 5–6). Error bars indicate SEM.