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Pharmacology of the glucose-response in orexin neurons. A, B, Current-clamp recordings showing the effect of external pH (pHe) on glucose-induced hyperpolarization in WT (A) and TASK−/− (B) neurons. C, D, Responses to glucose are reversed by Ba2+. Examples of the effects of 200 μm Ba2+ (C) or increasing Ba2+ concentrations (D) are shown. Recordings were obtained in control C57BL/6J mice.
