Table 2.

Effect of Ro15–4513 on GABA_A-R-mediated sIPSCs in granule cells of the dentate gyrus during pregnancy and after delivery

Group (n)	Amplitude (% change)	Decay time (% change)	Area (% change)	Frequency (% change)
E (5)	−5.5 ± 7.2	−24.1 ± 4.1*	−31.2 ± 9.5*	−11.2 ± 7.3
P19 (8)	−10.3 ± 6.8	−19.5 ± 5.2*	−23.1 ± 10.3*	−3.6 ± 6.9
pp2 (8)	12.2 ± 10.2	28.6 ± 8.3*	25 ± 11.5	−5.8 ± 7.7

Data are expressed as the percentage of change in current parameters induced by Ro15-4513 (3 μm) and are means ± SEM for the indicated numbers (n) of neurons in hippocampal slices obtained from rats in estrus, at day 19 of pregnancy, or at 2 d after delivery.

*p < 0.05 versus estrus (one-way ANOVA followed by Scheffe's test).