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. 2009 Feb 18;29(7):2089–2102. doi: 10.1523/JNEUROSCI.3567-08.2009

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Copyright © 2009 Society for Neuroscience 0270-6474/09/292089-14$15.00/0

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Figure 10. — Peripheral TNFα signaling stimulates microglia to produce MCP-1/CCL2 in day 5 BDR mice. Solid bars represent the percentage of total cerebral microglia that express MCP-1/CCL2 in day 5 BDR mice that had received either normal rabbit serum (NRS) or anti-TNFα serum intraperitoneally on days 2 and 4 postsurgery. Hatched bars represent the total number of MCP-1/CCL2-expressing cerebral microglia in day 5 BDR mice treated with either NRS or anti-TNFα serum on days 2 and 4 postsurgery. Error bars represent mean ± SEM of data from 4 NRS-treated BDR and 3 anti-TNFα serum-treated BDR mice; *p < 0.05 versus NRS-treated BDR mice.