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. 2019 Jul 26;11:7077–7087. doi: 10.2147/CMAR.S209940

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© 2019 Kondratyeva et al.

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Expression of PDX1 significantly reduces both migration and invasion of human pancreatic cancer cells. (А) Effect of PDX1 overexpression on pancreatic cancer cell wound recovery. Nearly confluent cell monolayers of PANC-1^Control and PANC-1^PDX1 cells were scratched, and wound recovery was monitored after 24 hrs. The rate of wound closure ± SEM is shown. The experiment was performed in triplicate with a similar trend. (B) The transwell cell invasion assay of PANC-1^Control and PANC-1^PDX1 cells. Representative fields of invasive cells on a membrane are captured. The average number of invasive cells per field from three independent experiments ± SEM is shown. *P<0.05; **P<0.01.