Fig. 4. Temporal multi-omics responses to immunization.
a, Heatmap showing different responses during RVI (n = 156 categorized time points) and immunization (n = 117 categorized time points, AUC test, two-sided, over the entire course of events and paired t-test, two-sided, for stage-wise comparison), same positions/labels as in Fig. 3. b, The ROC curve for classifiers designed to discriminate RVI time points from healthy baselines at different discrimination thresholds in testing data based on an LR model. 95% confidence intervals are shown as coloured ribbons. AUC scores of ROC curves are listed on the right for classification accuracy.