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. 2009 Jun 3;29(22):7220–7229. doi: 10.1523/JNEUROSCI.4362-08.2009

Figure 3.

Figure 3.

Substance P has no effect on spontaneous miniature IPSCs. A, Time course of miniature IPSC (mIPSC) rate during superfusion of substance P (SubP, 300 nm), met-enkephalin (ME, 10 μm), naloxone (NAL, 1 μm), and cadmium (Cd2+, 100 μm). B, Averaged traces of miniature IPSCs before (Pre) and during substance P and met-enkephalin. C, D, Cumulative probability (Cumul. Prob.) distribution plots of miniature IPSCs versus inter-event interval (C) and amplitude (D) before and during substance P and met-enkephalin. E, Representative raw traces before and during substance P and met-enkephalin. F, Bar chart of the mean rate and amplitude (Ampl) of miniature IPSCs in the presence of substance P, met-enkephalin, and DHPG (30 μm), expressed as a percentage of the predrug control (Ctl) level, in slices preincubated in standard (2.5 mm) and elevated (17.5 mm; Elevated [K+]o) extracellular [K+]. *p < 0.05; **p < 0.01. A–E are taken from one neuron in 17.5 mm [K+]o.