Figure 6.

The glutamate transport inhibitor TBOA occludes substance P effects on evoked IPSCs. A, Averaged traces of evoked IPSCs before (Pre) and during superfusion of TBOA (30 μm), TBOA + substance P (SubP, 300 nm), and TBOA + met-enkephalin (ME, 10 μm). B, Averaged traces of evoked IPSCs before and during DHK (200 μm) and DHK + substance P. C, Bar chart of the mean amplitude of evoked IPSCs (eIPSC Ampl) in the presence of substance P and met-enkephalin, expressed as a percentage of the predrug control (Ctl) level, in neurons preincubated in TBOA and DHK. *p < 0.05; **p < 0.01. A and B are taken from different neurons.