Table 3. Univariate analysis of predictors of CSS in patients with AA.
Risk Factors | N(%) | Univariate analysis | ||
---|---|---|---|---|
HR | HR (95% CI) | P Value | ||
Age | ||||
<50 | 26(19.12) | (-) | ||
≥50 | 110(80.88) | 1.27 | 0.62–2.60 | 0.522 |
Gender | ||||
Female | 51(37.5) | (-) | ||
Male | 85(62.5) | 1.07 | 0.61–1.88 | 0.807 |
Race | ||||
White | 102(75) | (-) | ||
Black | 20(14.71) | 1.47 | 0.71–3.04 | 0.299 |
Other | 14(10.29) | 0.83 | 0.29–2.33 | 0.720 |
Marital status | ||||
Married | 74(54.41) | (-) | ||
Single | 22(16.18) | 0.97 | 0.42–2.23 | 0.947 |
Divorce | 40(29.41) | 0.86 | 0.46–1.59 | 0.619 |
Histology | ||||
Adenocarcinoma | 108(79.41) | (-) | ||
Mucinous | 24(17.65) | 1.08 | 0.52–2.23 | 0.838 |
SRCC | 4(2.94) | 1.07 | 0.26–4.44 | 0.925 |
Grade | ||||
Well | 18(13.24) | (-) | ||
Moderate | 83(61.03) | 1.19 | 0.46–3.09 | 0.720 |
Poor | 35(25.74) | 2.18 | 0.81–5.90 | 0.123 |
No. of positive LN | ||||
0 | 22(16.18) | (-) | ||
1–3 | 61(44.85) | 2.93 | 1.55–5.53 | 0.001 |
≥4 | 53(38.97) | 4.24 | 2.08–8.62 | 0.000 |
Size (CM) | ||||
≤2 | 85(62.5) | (-) | ||
2–5 | 32(23.53) | 0.62 | 0.29–1.32 | 0.211 |
>5 | 19(13.97) | 1.01 | 0.49–2.07 | 0.985 |
Radiotherapy | ||||
Yes | 42(30.88) | (-) | ||
No | 94(69.12) | 1.61 | 0.84–3.08 | 0.150 |
Chemotherapy | ||||
Yes | 43(31.62) | (-) | ||
No | 93(68.38) | 1.30 | 0.71–2.39 | 0.390 |
SRCC: Signet Ring Cell Carcinoma; No: Number; LN: Lymph Node; RA: Rectal Adenocarcinoma; AA: Anal Adenocarcinoma