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. Author manuscript; available in PMC: 2019 Jul 30.
Published in final edited form as: Cell. 2019 Feb 7;176(5):967–981.e19. doi: 10.1016/j.cell.2018.12.039

Figure 2. Innate-like Vδ1+ IELs Are Lost in CeD.

Figure 2.

(A) Frequency of IELs expressing NKp46 with or without NKp44. Right: boxplots display first and third quartiles. ***p < 0.001. One-way ANOVA with Tukey’s test for multiple comparisons.

(B) Expression of NKp46 or NKp46/NKp44 on control Vδ1+ IELs versus age.

(C) Expression of NKp46 and NKp44 on Vδ1+ IELs from donor-matched duodenal and right colonic biopsies.

(D) Expression of CD107a on IL-15-treated IELs after stimulation with plate-bound αTCRγδ ± αNKp46. *p < 0.05. Paired t test.

(E) Expression of CD107a on Vδ1+ IELs after stimulation with phorbol myristate acetate and ionomycin. Right: boxplot displays first and third quartiles. **p < 0.01, ***p < 0.001. One-way ANOVA with Tukey’s test for multiple comparisons.

See also Figures S1 and S6.