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. Author manuscript; available in PMC: 2019 Jul 30.
Published in final edited form as: Cell. 2019 Feb 7;176(5):967–981.e19. doi: 10.1016/j.cell.2018.12.039

Figure 3. Dietary Gluten Drives the Emergence of IFN-γ-Producing Vδ1+ IELs in CeD.

Figure 3.

(A) Expression of IFN-γ and TNF-α in cells stimulated ex vivo with phorbol myristate acetate and ionomycin. Bottom: boxplots display first and third quartiles. *p < 0.05, **p < 0.01, ***p < 0.001. One-way ANOVA with Tukey’s test for multiple comparisons.

(B) Expression of IFN-γ and TNF-α in cells from patients with GFD-treated CeD stimulated as in (A) before and after gluten challenge. Duration of GFD: 1.5 years, 4 years, 7 years, and 20.5 years. Right: boxplots display first and third quartiles. *p < 0.05. Paired t test.

See also Figure S6.