Table 1:

Distribution of serum biomarkers in participants at risk of incident hearing impairment (N=1088)

	Aldosterone (ng/dL)			IGF1 (ng/mL)			BDNF (ng/mL)
	Mean	SD	Range	Mean	SD	Range	Mean	SD	Range
Overall	9.1	6.1	2.9 – 63.6	74.3	25.4	20.2 – 238.8	21.6	6.2	2.4 – 63.0
Sex†
Men	8.5	5.0	2.9 – 41.9	81.3	24.5	21.4 – 187.8	20.2	5.9	4.4 – 42.3
Women	9.4	6.5	2.9 – 63.6	71.2	25.1	20.2 – 238.8	22.2	6.3	2.4 – 63.0
Age (years)‡
53–59	8.1	5.4	2.9 – 60.5	75.1	25.0	21.4 – 187.8	21.6	6.2	4.7 – 63.0
60–69	9.2	5.9	2.9 – 63.6	72.7	24.3	23.0 – 219.3	21.8	6.4	6.8 – 60.6
70–79	10.8	7.6	2.9 – 58.6	77.2	28.6	32.7 – 238.8	20.9	6.0	2.4 – 34.3
80+	9.9	5.9	3.8 – 25.8	67.2	18.5	20.2 – 103.9	21.9	5.6	13.0 – 34.7

^†p-values for difference of biomarkers by sex (aldosterone: p=0.02, IGF1: p<0.0001, BDNF: p<0.0001)

^‡p-values for difference of biomarkers by age group (aldosterone: p<0.0001, IGF1: p=0.02, BDNF: p=0.11)