. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: Laryngoscope. 2019 Jan 30;129(9):2178–2183. doi: 10.1002/lary.27847

Table 4:

Difference in PTA change (dbHL) between Q1 and Q5 of Aldosterone, Insulin-like growth factor (IGF1), and Brain-derived neurotrophic factor (BDNF), overall and by sex^†

Aldosterone	PTA change 5 year follow-up		PTA change 10 year follow-up		PTA change 16 year follow-up
Aldosterone	Beta	p-value	Beta	p-value	Beta	p-value
Overall	0.11	0.80	0.11	0.87	−1.00	0.32
Men	1.49	0.04	−0.81	0.41	−1.49	0.31
Women	−0.58	0.29	0.65	0.47	−1.58	0.25
IGF1
IGF1
Overall	−0.66	0.14	−0.22	0.75	−0.72	0.49
Men	−1.88	0.01	−0.79	0.43	−0.20	0.90
Women	0.09	0.87	−0.04	0.97	−1.26	0.37
BDNF
BDNF
Overall	−0.11	0.79	1.26	0.06	0.04	0.97
Men	−0.15	0.85	1.82	0.07	1.93	0.20
Women	0.13	0.81	0.91	0.32	−1.38	0.33

^†

Overall models control for age and sex, sex specific models control for age. A positive beta indicates a larger change in PTA (decline in hearing) for those in Q1 versus Q5.