Cell viability of HepG2 cells exposed to different concentrations (10, 50, 100 μg/mL) of MSNs, MSNs-BSA, MSNs-Tf, MSNs-BSA-AgNPs and MSNs-Tf-AgNPs for 24 (A), 48 (B) and 72 (C) hours (n=5). Data were analyzed by ANOVA followed by Bonferroni´s multiple-comparison test. ***p < 0.001 versus MSNs-Tf. #p < 0.05. ##p < 0.01 ###p < 0.001 versus MSNs-BSA-AgNPs.