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. Author manuscript; available in PMC: 2020 Mar 7.
Published in final edited form as: Nanoscale. 2019 Mar 7;11(10):4531–4545. doi: 10.1039/C8NR07667G

Table 5. Deregulated proteins obtained in the SILAC study after HepG2 cells exposure to the MSNs-Tf-AgNPs nanosystem.

gi number Protein name Common name RSILAC RSDSILAC
194394237 Villin-1 [Homo sapiens] VIL1 -3.34 13.73
119226260 Calcium homeostasis endoplasmic reticulum protein [Homo sapiens] CHERP -2.85 4.69
261862348 Serine hydroxymethyltransferase, mitochondrial isoform 3 [Homo sapiens] SHMT2 -2.26 17.30
4506489 Replication factor C subunit 3 isoform 1 [Homo sapiens] RFC3 -1.91 18.71
4557469 AP-2 complex subunit beta isoform b [Homo sapiens] AP2B1 -1.90 8.30
56237027 Insulin-like growth factor 2 mRNA-binding protein 1 isoform 1 [Homo sapiens] IGF2BP1 -1.78 9.63
301171467 ATP-dependent RNA helicase DDX3X isoform 2 [Homo sapiens] DDX3X -1.77 19.17
98986457 Host cell factor 1 [Homo sapiens] HCFC1 -1.67 11.74
4506701 40S ribosomal protein S23 [Homo sapiens] RPS23 -1.65 10.25
11321585 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [Homo sapiens] GNB1 -1.61 14.35
5453740 Myosin regulatory light chain 12A [Homo sapiens] MYL12A -1.61 18.81
116256489 Septin-9 isoform c [Homo sapiens] SEPT9 -1.59 18.39
4505917 Exosome component 10 isoform 2 [Homo sapiens] EXOSC10 -1.59 11.80
15011936 40S ribosomal protein S26 [Homo sapiens] RPS26 -1.56 3.97
4504897 Importin subunit alpha-2 [Homo sapiens] KPNA2 -1.56 19.75
189491630 Upstream-binding protein 1 isoform LBP-1b [Homo sapiens] UBP1 -1.54 19.34
24497603 Nuclear pore glycoprotein p62 [Homo sapiens] NUP62 -1.50 19.29
10800130 Histone H2A type 1-D [Homo sapiens] HIST1H2AD 1.50 10.32
5453994 Double-strand-break repair protein rad21 homolog [Homo sapiens] RAD21 1.57 19.53
118601081 Heterogeneous nuclear ribonucleoprotein U-like protein 2 [Homo sapiens] HNRNPUL2 1.60 4.51
4505343 Nuclear cap-binding protein subunit 1 [Homo sapiens] NCBP1 1.60 12.42
10863903 E3 ubiquitin-protein ligase TRIP12 [Homo sapiens] TRIP12 1.62 1.16
4503571 Alpha-enolase isoform 1 [Homo sapiens] ENO1 1.68 2.87
89179321 Protein unc-45 homolog A isoform 3 [Homo sapiens] UNC45A 1.68 11.73
283436222 ATPase family AAA domain-containing protein 3A isoform 2 [Homo sapiens] ATAD3A 1.71 6.41
4503529 Eukaryotic initiation factor 4A-I isoform 1 [Homo sapiens] EIF4A1 1.71 19.97
4506675 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor [Homo sapiens] RPN1 1.78 0.75
19923653 PC4 and SFRS1-interacting protein isoform 1 [Homo sapiens] PSIP1 1.93 16.95
101943240 General transcription factor 3C polypeptide 1 [Homo sapiens] GTF3C1 2.12 15.46
14589866 Aspartyl/asparaginyl beta-hydroxylase isoform a [Homo sapiens] ASPH 2.21 14.65
45593130 Guanine nucleotide-binding protein-like 3 isoform 1 [Homo sapiens] GNL3 2.58 8.80
148839305 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [Homo sapiens] SMCHD1 2.66 7.37