Table 3.

Target Infliximab trough Drug Level from Various Studies

Study	Year	Disease	Design	No. of subjects	Assay	Threshold (µg/mL)
Steenholdt et al. [143]	2011	IBD	Obs	106	RIA	≥ 2.8
Bortlik et al. [144]	2013	CD	Obs	84	ELISA	≥ 3.0
Cornillie et al. [99]	2014	CD	RCT	144	ELISA	≥ 3.5
Adedokun et al. [145]	2014	UC	RCT	728	ELISA	≥ 3.7
Levesque et al. [146]	2014	CD	Obs	327	HMSA	≥ 3.0
Vande Casteele et al. [147]	2015	CD	Obs	483	HMSA	≥ 2.8
Reinisch et al. [148]	2015	CD	RCT	203	ELISA	≥ 3.0
Vande Casteele et al. [149]	2015	IBD	RCT	263	ELISA	≥ 3.7

Obs, observational; RIA, radioimmunoassay; RCT, randomized controlled trail; HMSA, homogeneous mobility shift assay.