Table 3.
Relative bile acid profiles of the serum
| (%) | ||||
|---|---|---|---|---|
| Control | HFD | HFD + EGCG | ||
| Free- | Cholic acid | 19.66 ± 3.32 | 9.83 ± 2.46* | 22.97 ± 5.45† |
| ω-Muricholic acid | 11.90 ± 4.29 | 3.08 ± 0.87* | 13.44 ± 3.58† | |
| α-Muricholic acid | 2.09 ± 0.75 | 0.91 ± 0.72 | 1.47 ± 1.03 | |
| β-Muricholic acid | 8.70 ± 2.73 | 10.19 ± 5.25 | 9.47 ± 5.76 | |
| Chenodeoxycholic acid | 2.49 ± 1.20 | 2.51 ± 0.71 | 4.35 ± 1.52*,† | |
| Deoxycholic acid | 24.01 ± 5.82 | 38.83 ± 6.07* | 33.16 ± 9.47 | |
| Lithocholic acid | 5.46 ± 2.44 | 2.92 ± 1.47 | 3.95 ± 1.40 | |
| Ursodeoxycholic acid | 3.17 ± 1.81 | 1.12 ± 0.64* | 0.85 ± 0.50* | |
| Ursocholic acid | 0.35 ± 0.17 | 0.08 ± 0.10* | 0.09 ± 0.11* | |
| Hyocholic acid | 0.03 ± 0.04 | 0.01 ± 0.02 | 0.09 ± 0.19 | |
| Murideoxycholic acid | 0.14 ± 0.11 | 0.33 ± 0.14 | 0.42 ± 0.20* | |
| Hyodeoxycholic acid | 2.45 ± 0.60 | 1.18 ± 0.75* | 1.14 ± 0.33* | |
| Isodeoxycholic acid | 1.65 ± 0.71 | 1.12 ± 0.88 | 0.84 ± 0.23 | |
| 3-Dehydrocholic acid | 0.13 ± 0.11 | 0.03 ± 0.03 | 0.21 ± 0.25 | |
| 7-Oxodeoxycholic acid | 4.60 ± 1.85 | 0.87 ± 0.57* | 1.00 ± 0.46* | |
| 3-Dehydrodeoxycholic acid | 0.03 ± 0.03 | 0.08 ± 0.06 | 0.16 ± 0.15 | |
| 12-Oxolithocholic acid | 1.52 ± 0.88 | 0.80 ± 0.50 | 1.01 ± 0.34 | |
| Free-bile acid | 88.38 ± 7.12 | 73.90 ± 3.10* | 94.62 ± 2.10† | |
| Glyco- | Cholic acid | 0.09 ± 0.04 | 0.30 ± 0.65 | 0.04 ± 0.04 |
| Chenodeoxycholic acid | 0.08 ± 0.06 | 0.02 ± 0.02 | 0.05 ± 0.07 | |
| Deoxycholic acid | 0.02 ± 0.02 | 0.01 ± 0.01 | 0.15 ± 0.20 | |
| Lithocholic acid | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.01 ± 0.01 | |
| Ursodeoxycholic acid | 0.02 ± 0.04 | 0.00 ± 0.00 | 0.01 ± 0.02 | |
| Glyco-bile acid | 0.22 ± 0.09 | 0.32 ± 0.64 | 0.27 ± 0.26 | |
| Tauro- | Cholic acid | 6.33 ± 4.05 | 16.80 ± 6.42* | 1.97 ± 1.98† |
| ω-Muricholic acid | 2.09 ± 2.04 | 0.59 ± 0.62 | 0.64 ± 0.43 | |
| α-Muricholic acid | 0.59 ± 0.72 | 0.55 ± 0.52 | 0.34 ± 0.62 | |
| β-Muricholic acid | 2.09 ± 1.47 | 4.84 ± 3.23 | 0.90 ± 1.24† | |
| Chenodeoxycholic acid | 0.05 ± 0.04 | 0.13 ± 0.05 | 0.20 ± 0.20 | |
| Deoxycholic acid | 0.16 ± 0.20 | 2.73 ± 1.88* | 0.87 ± 0.83† | |
| Lithocholic acid | 0.03 ± 0.03 | 0.03 ± 0.04 | 0.04 ± 0.06 | |
| Ursodeoxycholic acid | 0.08 ± 0.08 | 0.11 ± 0.14 | 0.13 ± 0.17 | |
| Tauro-bile acid | 11.41 ± 7.05 | 25.78 ± 3.28* | 5.11 ± 2.16† | |
C57BL/6N mice were fed with the control CE-2 diet (control), a high-fat diet (HFD), or the HFD supplemented with 0.32% EGCG (HFD + EGCG) for 8 weeks. Values are expressed as the means ± SEM (%) of six mice in each group; *p<0.05 compared with the Control group. †p<0.05 compared with the HFD group.