Table 3.
Positive and negative predictive values for PSMA-11 PET/CT(MRI) in 65 patients in relation to PSA level at the time of imaging
| PSA level at the time of SLND (ng/ml)a | ||||
|---|---|---|---|---|
| <1.4 | ≥1.4 | |||
| Positive predictive value (95% CI), % | Negative predictive value (95% CI), % | Positive predictive value (95% CI), % | Negative predictive value (95% CI), % | |
| Regional analysis | ||||
| Pelvic (right) | 95 (74.2–99.2) | 100 | 100 | 85.7 (61.7–95.7) |
| Pelvic (left) | 94.4 (71.8–99.1) | 100 | 100 | 100 |
| Presacral | 100 | 97 (84.2–99.9) | 93.3 (67.5–99) | 94.1 (70.6–99) |
| Retroperitoneal | 100 | 96.7 (84.2–99.4) | 100 | 92.6 (79.5–97.6) |
| Subregional analysis | ||||
| Common iliac | ||||
| Right | 50 (7.1–92.9) | 90.3 (84.1–94.3) | 100 | 80 (63.1–90.3) |
| Left | 80 (34.5–96.8) | 89.3 (77.9–95.2) | 100 | 100 |
| External iliac | ||||
| Right | 100 | 96.2 (80–99.4) | 100 | 92.6 (79.5–97.6) |
| Left | 85.7 (46.7–97.6) | 100 | 100 | 96 (79.3–99.3) |
| Internal iliac | ||||
| Right | 100 | 96.3 (80.9–99.4) | 100 | 100 |
| Left | 100 | 90.9 (73.7–97.3) | 100 | 95.7 (77.4–99.3) |
| Obturator | ||||
| Right | 100 | 96.2 (80–99.4) | 100 | 95.5 (76.4–99.3) |
| Left | 100 | 96.3 (80.9–99.4) | 100 | 90.9 (73.8–97.3) |
| External, internal and obturator combined | ||||
| Right | 100 | 100 | 100 | 93.3 (67.6–99) |
| Left | 95 (74.2–9.2) | 100 | 100 | 100 |
a33 patients with a PSA level <1.4 ng/ml, median 0.8 ng/ml (IQR 0.6–1 ng/ml); 32 patients with a PSA level ≥1.4 ng/ml, median 2.9 ng/ml (IQR 2.3–4.2 ng/ml)