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. 2019 Jul 30;10:3298. doi: 10.1038/s41467-019-10914-6

Table 2.

Incidence of anti-allergic drug prescription in patients after prescription of gastric acid inhibitors or control medications

Person-years # with anti-allergic prescription Incidence rate % Rate ratio p-value
Persons with previous gastric acid inhibitor prescription
Total 117,287 7706 6.57 (6.42–6.72) 3.07 (2.89–3.27) <0.001
Males 46,002 2383 5.18 (4.97–5.39) 2.93 (2.66–3.22) <0.001
Females 71,285 5323 7.47 (7.27–7.67) 2.92 (2.69–3.17) <0.001
Age < 20 y 9,543 1058 11.09 (10.42–11.75) 2.04 (1.20–3.45) 0.008
 20–39 y 48,502 3636 7.50 (7.25–7.74) 2.41 (2.01–2.91) <0.001
 40–59 y 47,097 2467 5.24 (5.03–5.44) 2.52 (2.30–2.77) <0.001
 ≥60 y 12,145 545 4.49 (4.11–4.86) 2.22 (1.96–2.51) <0.001
Persons with previous C09/C10 prescription
Total 53,793 1151 2.14 (2.02–2.26)
Males 28,549 505 1.77 (1.61–1.92)
Females 25,244 646 2.56 (2.36–2.76)
Age < 20 y 257 14 5.45 (2.59–8.30)
  20–39 y 3,704 115 3.10 (2.54–3.67)
  40–59 y 26,190 544 2.08 (1.90–2.25)
  ≥60 y 23,642 478 2.02 (1.84–2.20)

Incidence rates and 95% confidence intervals (CI) of anti-allergic drug prescriptions in individuals with acid inhibitor medication and with anti-hypertensive or lipid-modifying (C09/C10) drug prescriptions from data of the Austrian county Burgenland and rate ratios for an anti-allergic prescription in individuals with acid inhibitor medication relative to those with C09/C10 prescriptions. p values based on Wald chi-square test