Skip to main content
. 2019 Jun 8;26:18–29. doi: 10.1016/j.molmet.2019.06.001

Figure 8.

Figure 8

Effect of central CF-RELN administration on c-Fos expression, food intake, and body weight. A, Representative immunohistochemistry images of c-Fos expression in the ARH of vehicle (n = 6) and CF-RELN (n = 5) treated mice. B, Average number of c-Fos + neurons in the ARH per section (unpaired t-test). C, Daily and delta (D) food intake after daily lateral ventricle ICV administration of vehicle (n = 6), or CF-RELN at 0.15 nmol/day (n = 6; p = 0.001), 0.30 nmol/day (n = 5), or 0.625 nmol/day (n = 6; p = 0.02; two-way ANOVA Dunnett's post-hoc) E, Daily and delta (F) body weight measured in animals injected with vehicle (n = 6), or CF-RELN at 0.15 nmol/day (n = 6; p = 0.02), 0.30 nmol/day (n = 5), or 0.625 nmol/day (n = 6; two-way ANOVA Dunnett's post-hoc; Error bars indicate ± SEM; *p < 0.05, **p < 0.01).