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. 2019 Jul 24;10:503. doi: 10.3389/fendo.2019.00503

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Copyright © 2019 Riccetti, Sperduti, Lazzaretti, Klett, De Pascali, Paradiso, Limoncella, Potì, Tagliavini, Trenti, Galano, Palmese, Satwekar, Daolio, Nicoli, Villani, Aguzzoli, Reiter, Simoni and Casarini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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STARD1 and CYPA19A1 gene expression analysis. The expression of STARD1 (A) and CYPA19A1 (B) gene was evaluated in hGLC stimulated for 12 h with the EC₅₀ of Gonal-f® or biosimilars (12 ng/ml Gonal-f® and Ovaleap®, 24 ng/ml Bemfola®) by real-time PCR. Each value was normalized over the RPS7 gene expression (means ± SEM; n = 4). Unstimulated cells served as control and are indicated as a dotted line. (*= significant vs. Bemfola®, Kruskal Wallis test; p < 0.05).