. 2019 Jul 24;10:503. doi: 10.3389/fendo.2019.00503

Table 5.

Efficiency (EC₅₀) of 30 min-cAMP and β-arrestin 2 production induced by reference and biosimilar follitropin alfa preparations in transfected, FSHR-expressing HEK293 cells.

Preparation	EC₅₀ cAMP (ng/ml; means ± SEM; n = 4)	*p^a*	EC₅₀ β-arrestin 2 (ng/ml; means ± SEM; n = 4)	p^a
Gonal-f®	12.9 ± 2.5	0.561	278.6 ± 56.9	0.223
Ovaleap®	14.7 ± 3.9		140.7 ± 42.6
Bemfola®	24.2 ± 6.0		234.9 ± 57.2

Kruskal-Wallis test.