Table 1.
Rapid Point-of-Care vs Standard Technique Test During the 2017–2018 Flu Season: Sociodemographic Characteristics, Biologic Values, and End Point Results
| Alere-i (POC NAAT) n = 72 | Standard RT-PCR n = 106 | P Value | |
|---|---|---|---|
| Age, y | 63 (25–92) | 66 (22–95) | NS |
| M/F | 35/37 | 56/50 | NS |
| Viral strains A/B | 25/47 | 28/78 | NS |
| High-risk factors | 38 (52.8) | 69 (65.1) | NS |
| Deaths | 1 (1.4) | 4 (3.8) | NS |
| ICU | 3 (4.2) | 1 (0.9) | NS |
| Leucocytes, giga/L | 7.09 (1.98–17.40) | 7.41 (2.02–17.72) | NS |
| CRP, mg/L | 50 (2–448) | 65 (1–608) | NS |
| Microbiology | 1 sputum culture + a | 3 blood cultures + b | |
| Oseltamivir treatment | 41 (56.9) | 66 (62.3) | NS |
| Time of 1st NI delivery, h min | 9h32 (1h41–53h54) | 23h41 (1h39–101h32) | <.001 |
| Antibiotic treatment | 28 (38.9) | 59 (55.7) | .03 |
| Time of 1st ab delivery, h min | 37h57 (1h19–300h57) | 19h32 (1h22–224h58) | NS |
| Duration, d | 6 (1–15) | 6 (1–13) | NS |
| Duration of stay (ED), h min | 10h17 (1h00–52h56) | 12h52 (0h50–59h15) | .005 |
| Hospitalization | 28 (38.9) | 65 (61.3) | .003 |
| Duration, d | 8.5 (2–33) | 7.9 (1–29) | NS |
| Isolation measures | 22 (78.5) | 40 (61.5) | NS |
Data are presented as No., mean (range), or No. (%). P values* significant differences if P <0.05.
Abbreviations: ab, antibiotic; CRP, C-reactive protein; ED, emergency department; ICU, intensive care unit; NAAT, nucleic-acid amplification test; NI, neuraminidase inhibitors; NS, not significant; POC, point-of-care; RT-PCR, reverse transcription polymerase chain reaction.
a Staphylococcus aureus.
b Staphylococcus aureus (1), Haemophilus influenzae (1), Staphylococcus epidermidis (1).