Table 1.
Medications with ≥ 1% of Total VA Insomnia Medication Utilization in VA in 2011–2012
| Class and agent | FDA-approved for insomnia | Suicidal ideation/behavior warning on the label | Utilization, 2011–2012 | |
|---|---|---|---|---|
| Unique patients (n, %) | Fills (mean, SD) | |||
| Hypnotics, miscellaneous | ||||
| Zolpidem | Yes | Yes | 354,413 (20) | 7.88 |
| Benzodiazepines | ||||
| Lorazepam | No | Yes | 225,057 (13) | 8.12 |
| Temazepam | Yes | No | 131,296 (8) | 8.95 |
| Diazepam | No | No | 118,067 (7) | 8.52 |
| Antidepressant, serotonin reuptake inhibitor/agonist | ||||
| Trazodone | No | Yes | 507,370 (29) | 6.56 |
| Antihistamine, first generation10 | ||||
| Diphenhydramine | No | No | 142,574 (8) | 3.58 |
| Hydroxyzine | No | No | 264,083 (15) | 4.49 |