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. 2019 Jul 24;13:779. doi: 10.3389/fnins.2019.00779

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Copyright © 2019 Ferdousi, Sasaki, Uchida, Ohkohchi, Zheng and Isoda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional analysis of DEGs between RA-treated (T7) and day 7 untreated control (D7) hAECs. (A) Changes in the expression of epigenetic modifiers by RA treatment (T7) compared with untreated-control on day 7 (D7); (B) Significantly enriched cellular components (p < 0.05; modified Fisher’s exact test); (C) Top molecular functions as per p-Value (modified Fisher’s exact) by downregulated genes. (D) Top molecular functions as per p-Value (modified Fisher’s exact) by upregulated genes. (E) Significantly enriched KEGG pathways by downregulated genes (p < 0.05; modified Fisher’s exact test). (F) Significantly enriched psychological and neurological diseases (p < 0.05; modified Fisher’s exact test).