. 2019 Jul 24;13:779. doi: 10.3389/fnins.2019.00779

TABLE 1.

Significantly enriched gene sets by DEGs between RA treated and control cells.

Gene Set Name^*	Systematic name, exact source	No. of genes in set	No. of genes in overlap	p-value	Adjusted p-value
Significantly enriched gene sets by DEGs between RA treated (T7) and control cells (D0)
HALLMARK¹_G2M_CHECKPOINT²		200	81	2.56 e^–46	1.28 e^–44
HALLMARK_E2F_TARGETS³		200	70	2.38 e^–35	5.94 e^–34
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION		200	58	1.01 e^–24	1.01 e^–23
GO_CELL_CYCLE	M14460, GO:0007049	1316	284	5.72 e^–84	3.39 e^–80
GO_CYTOSKELETON	M17350, GO:0005856	1967	351	2.33 e^–80	6.95 e^–77
GO_REGULATION_OF_CELL_DIFFERENTIATION	M13423, GO:0045595	1492	236	3.55 e^–44	5.88 e^–42
GO_NEUROGENESIS	M13908, GO:0022008	1402	206	6.57 e^–34	5.05 e^–32
Significantly enriched gene sets by DEGs between RA treated (T7) and control cells (D7)
GO_NEUROLOGICAL_SYSTEM_PROCESS	M10152, GO:0050877	1242	133	3.36 e^–35	1.71 e^–32
GO_NEUROGENESIS	M13908, GO:0022008	1402	141	2.47 e^–34	1.09 e^–31
GO_REGULATION_OF_CELL_DIFFERENTIATION	M13423, GO:0045595	1492	142	5.11 e^–32	1.8 e^–29
GO_NEURON_DIFFERENTIATION	M15330, GO:0030182	874	92	4.8 e^–24	6.81 e^–22

^*GSEA online software (http://software.broadinstitute.org/gsea/index.jsp). ¹Hallmark gene sets summarize and represent specific well-defined biological states or processes and display coherent expression. ²Genes involved in the G2/M checkpoint, as in progression through the cell division cycle. ³Genes encoding cell cycle related targets of E2F transcription factors.