Skip to main content
. 2019 Apr 24;220(5):862–872. doi: 10.1093/infdis/jiz206

Figure 2.

Figure 2.

PLA2G4B locus is associated with candidemia susceptibility. (A) Manhattan plot of single-nucleotide polymorphisms (SNPs) associated with candidemia susceptibility identified by the genome-wide association study (GWAS). The GWAS revealed a locus strongly associated with susceptibility to candidemia at chromosome 15 (P = 7.97 × 10–8, odds ratio = 0.4002). The y-axis represents –log10P values of SNPs. The x-axis shows chromosomal positions. The blue line is the suggestive threshold for association (P < 9.99 × 10–5). (B) The regional association plot for the candidemia-associated SNP, rs8028958 (purple diamond), which is located within the intronic region of the SPTBN5 gene at chromosome 15. Each dot represents an SNP, and the linkage disequilibrium of neighboring SNPs with the top SNP is color coded. The y-axis represents –log10P values of SNPs. The x-axis shows chromosomal positions.