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. 2019 Jun 29;14:222–232. doi: 10.1016/j.omto.2019.06.002

Figure 6.

Figure 6

The DPDL1E Vaccine Increased the Levels of TILs and the Ratio of CD8+ T Cells/MDSCs in Tumor Tissues

(A and B) Tumor tissues isolated from mice of preventive groups (A) and therapeutic groups (B) were stained with anti-CD8α monoclonal antibody. The IOD was determined by Image-Pro Plus 4.5 software. (C) TILs were further confirmed using FCM. (D)The ratio of CD3+ CD8+ T cells in CD45+ was analyzed using FCM. (E) The ratio of MDSCs in CD45+ was also analyzed using FCM. (F) The ratio of CD8+ T cells/MDSCs was calculated and analyzed. Student’s t test was used to determine statistically significant differences. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.