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. 2019 Jul 24;10:477. doi: 10.3389/fendo.2019.00477

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Copyright © 2019 Akirov, Fazelzad, Ezzat, Thabane and Sawka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Meta-regression plots examining for any dose-response relationship between combination therapy dose and treatment preference over L-T4 monotherapy (L-T4 monotherapy during or before trial). (A) Total daily L-T3 dosage (ug) on combination therapy. (B) Ratio of L-T3 divided by L-T4 dosage (ug) on combination therapy.