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Effects of CYP3A5 on the phenotypes of SCC9 cells. (A) CYP3A5 expression was significantly downregulated in SCC9 cells following transfection with CYP3A5 siRNA when compared with NC. Knockdown of CYP3A5 in SCC9 cells promoted (B) cell proliferation and (C) invasion. *P<0.05, **P<0.01; ns, not significant; NC, negative control; CYP3A5, cytochrome P450 family 3 subfamily A member 5; siRNA, small interfering.
