Figure 2.
Plasma levels of 5-FU in the patients with different tumor responses after the start of continuous infusion. Blood samples of patients in (A) the partial response/stable disease group and (B) the progressive disease group were collected prior to the start of infusion (0 h), 22 and 40 h after the start of continuous 5-FU infusion, and 5-FU plasma levels were measured. The plasma levels of 5-FU of the partial response/stable disease group (n=9) and the progressive disease group (n=6) are presented as box-and-whisker plots. Values are compared among 0, 22 and 40 h. *P<0.05, **P<0.01, ***P<0.001. 5-FU, 5-fluorouracil.