Table II.
Tumor response | mFOLFOX6 (n=6) | FOLFIRI (n=9) | P-value |
---|---|---|---|
Complete response | 0 | 0 | N/A |
Partial response | 2 | 3 | >0.99 |
Stable disease | 1 | 3 | 0.60 |
Progressive disease | 3 | 3 | 0.52 |
Response rate | 33% | 33% | >0.99 |
Disease control rate | 50% | 67% | 0.52 |
In total, 6 patients were treated with the mFOLFOX6 regimen and 9 patients were treated with the FOLFIRI regimen. The number of patients with different tumor responses (complete response, partial response, stable disease and progressive disease) in each regimen are listed. The response rate is defined as the proportion of patients with complete or partial response among each regimen. The disease control rate is defined as the proportion of patients with complete, partial response or stable disease among each regimen. Statistical significance was determined by a bivariate analysis. There was no significant difference in each tumor response, response rate or disease control rate between the two regimens. mFOLFOX, modified 5-fluorouracil plus folinic acid-oxaliplatin; FOLFIRI, 5-fluorouracil plus folinic acid-irinotecan; N/A, not applicable.