Table II.

Differential expression analysis and survival analysis of KIF family genes in patients with LUAD.

	Differential expression analysis			Survival analysis
Genes	log2 Fold change	P-value	FDR	HRa	Low 95% CI	High 95% CI	P-valueb
KIF14	3.761199	<0.0001	<0.0001	1.686098	1.246964	2.279878	0.000689
KIF18A	1.373027	0.002178	0.00919	1.610726	1.190265	2.179715	0.002012
KIF23	2.582725	<0.0001	<0.0001	1.51088	1.117299	2.043104	0.007355
KIF20A	3.14896	<0.0001	<0.0001	1.478097	1.092943	1.998979	0.011181
KIF11	2.689239	<0.0001	<0.0001	1.437782	1.064161	1.94258	0.01803
KIF20B	1.301735	<0.0001	0.000271	1.43011	1.059873	1.929678	0.019265
KIF18B	3.766396	<0.0001	<0.0001	1.421903	1.052975	1.920092	0.021631
KIF4A	3.830272	<0.0001	<0.0001	1.405441	1.04261	1.894539	0.025494
KIF1B	0.008518	0.925271	0.972874	0.749876	0.558315	1.007161	0.055805
KIF27	−0.11005	0.603581	0.758646	0.763263	0.567524	1.02651	0.073954
KIFC1	2.734491	<0.0001	<0.0001	1.307037	0.968747	1.763459	0.079741
KIF4B	1.122955	0.585909	0.74532	1.282052	0.954614	1.721803	0.098684
KIFC2	1.792038	<0.0001	<0.0001	0.79411	0.590222	1.068429	0.127819
KIF2C	3.573061	<0.0001	<0.0001	1.25987	0.93572	1.696312	0.127964
KIFAP3	−0.1271	0.49553	0.668045	0.820523	0.610544	1.102719	0.189646
KIF16B	−0.04692	0.831639	0.914865	0.822771	0.611296	1.107406	0.198118
KIF1BP	0.032733	0.883941	0.946259	1.196995	0.890981	1.608112	0.232603
KIF13A	−0.5605	0.00104	0.00482	0.838206	0.624352	1.125311	0.240241
KIF5A	2.712286	0.007712	0.026645	0.850435	0.633679	1.141335	0.280467
KIF17	−1.99907	<0.0001	0.000566	0.854866	0.637723	1.145947	0.29427
KIF21B	0.316249	0.296082	0.472991	0.863796	0.641166	1.163729	0.335624
KIF3C	1.08788	0.000112	0.000682	1.155325	0.860101	1.551884	0.337567
KIF21A	0.471146	0.078692	0.175791	0.869257	0.647914	1.166216	0.35006
KIF5B	−0.11057	0.509291	0.680306	1.149144	0.857356	1.540238	0.352275
KIF26A	−1.46358	0.000133	0.000793	0.877007	0.652637	1.178514	0.38403
KIF12	1.77177	<0.0001	<0.0001	0.878517	0.6541	1.179931	0.389461
KIF24	0.658401	0.275437	0.450236	1.132135	0.843729	1.519126	0.408083
KIF15	2.685009	<0.0001	<0.0001	1.133063	0.842076	1.524602	0.40941
KIF25	1.190456	0.336607	0.51667	0.918596	0.685346	1.23123	0.569947
KIF7	0.621628	0.265307	0.439337	1.083857	0.807299	1.455156	0.592125
KIF6	−1.28474	0.013328	0.042003	0.924712	0.688201	1.242503	0.603526
KIF13B	−0.09452	0.4315	0.610314	1.07943	0.804877	1.447637	0.609761
KIF19	−1.23658	0.000403	0.002133	0.931921	0.694829	1.249914	0.637848
KIF5C	1.444426	0.067916	0.156645	0.937923	0.697936	1.260429	0.670823
KIF26B	3.141348	<0.0001	<0.0001	0.938876	0.698727	1.261564	0.675623
KIF1A	5.445563	<0.0001	<0.0001	1.064054	0.791266	1.430885	0.681207
KIF2A	0.760907	0.001016	0.004726	1.062085	0.791335	1.42547	0.688285
KIF22	1.166602	<0.0001	<0.0001	1.057282	0.787208	1.420012	0.711293
KIFC3	0.108768	0.504868	0.675814	1.056382	0.787667	1.41677	0.714182
KIF3B	−0.13168	0.409013	0.588436	0.954955	0.712533	1.279855	0.757712
KIF3A	−0.14052	0.500277	0.671849	0.955389	0.71235	1.281346	0.760587
KIF1C	−1.31875	<0.0001	<0.0001	0.990563	0.737947	1.329656	0.949668
KIF9	−0.34716	0.253979	0.425275	0.992495	0.739871	1.331377	0.959913

^aLow expression group is the reference group

^badjusted for tumor stage in the Cox proportional hazard regression model. KIF, kinesin; LUAD, lung adenocarcinoma; FDR, false discovery rate; HR, hazard ratio; CI, confidence interval.