Table 4.

Pairwise correlation between change in DAS28CRP, Krenn score, EULAR-OMERACT US combined score and RAMRIS MRI synovitis score of the RCJ of the wrist during the study

All patients with RA All visits	ΔKrenn score	ΔLarsen score*	ΔEO US combined	ΔEO US Doppler	ΔEO US GS	ΔMRI synovitis†	ΔMRI erosions	ΔMRI BM oedema
ΔDAS28CRP	r=0.25 p=0.12	r=0.18 p=0.29	r= 0.38 p= 0.02	r= 0.45 p= 0.004	r= 0.35 p= 0.02	r= 0.52 p= 0.02	r=−0.12 p=0.61	r=0.34 p=0.16
ΔKrenn score	–	r=0.01 p=0.95	r= 0.65 p< 0.001	r= 0.51 p< 0.001	r= 0.63 p< 0.001	r= 0.50 p= 0.03	r=−0.20 p=0.39	r=0.14 p=0.55
ΔLarsen score*		–	r=0.06 p=0.71	r=−0.04 p=0.81	r=0.05 p=0.77	r=0.14 p=0.58	r=0.06 p=0.82	r=0.06 p=0.81
ΔEO US combined			–	r= 0.66 p< 0.001	r= 0.96 p< 0.001	r= 0.59 p< 0.001	r=−0.52 p= 0.02	r=−0.11 p=0.67
ΔEO US Doppler				–	r= 0.62 p< 0.001	r= 0.61 p= 0.005	r=−0.38 p=0.09	r=0.07 p=0.76
ΔEO US GS					–	r= 0.67 p= 0.001	r=−0.53 p= 0.02	r=−0.08 p=0.74
ΔMRI synovitis†						–	r=−0.27 p=0.24	r=−0.15 p=0.54
ΔMRI erosions							–	r=0.00 p=1.00

ΔChange between 6-month visit and baseline visit data.

Comparison by unadjusted linear regression.

*Total Larsen wrist score (all quadrants).

†Only the ERA group underwent two MRI scans. Significant correlations in bold.

BM, bone marrow; EO, EULAR-OMERACT;ERA, early rheumatoid arthritis; GS, grey scale; RCJ, radiocarpal joint; US, ultrasound.