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. 2019 Jul 26;11:7111–7122. doi: 10.2147/CMAR.S201341

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© 2019 Yang et al.

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The combination of silibinin promotes A2780/DDP cells apoptosis. (A) silibinin (50 μM), cisplatin (115 μM), taxol (50 μM) and silibinin (50 μM) plus cisplatin (115 μM) and/or taxol (50 μM) treatment induces apoptosis of A2780/DDP cells. Apoptotic cells were assayed by Annexin V/PI staining and FACS analysis. (B) Quantification of (A). The Bar chart of all data represents mean ± SD of three independent experiments, ***p<0.001 vs control group.